Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GHSR | Q92847 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29932095 | 0.93 | LMNA (0.40) | MCOLN2KMT2AKDM4ELMNAKDM4C | |
| SCHEMBL23555092 | 0.91 | MCOLN2 (0.36) | MCOLN2KMT2AKDM4ELMNAKMO | |
| SCHEMBL29932183 | 0.89 | ALDH1A1 (0.41) | MCOLN2KMT2AKDM4ELMNARXFP1 | |
| SCHEMBL23536204 | 0.89 | ALDH1A1 (0.41) | MCOLN2KMT2AKDM4ELMNARXFP1 | |
| SCHEMBL23536479 | 0.89 | MCOLN2 (0.48) | MCOLN2KMT2AKDM4ELMNAKMO | |
| SCHEMBL23536230 | 0.87 | MCOLN2 (0.39) | MCOLN2KMT2AKDM4ELMNAKMO | |
| SCHEMBL29931978 | 0.86 | CRHBP (0.34) | MCOLN2KMT2ALMNAKMOCXCR2 | |
| SCHEMBL23555120 | 0.86 | MCOLN2 (0.37) | MCOLN2KMT2AKMOCXCR2GHSR | |
| SCHEMBL23536384 | 0.86 | CRHBP (0.34) | MCOLN2KMT2ALMNAKMOCXCR2 | |
| SCHEMBL29932066 | 0.83 | ALDH1A1 (0.38) | KMT2AKDM4ELMNACXCR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087440-A | TRPML modulators | 卡斯玛治疗公司 | 2022-09-20 | — | — | CN | disclosed |