Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536616 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRSMN1; SMN2MEN1 | |
| SCHEMBL23536635 | 0.72 | HSD17B10 (0.48) | ALDH1A1KDM4ETSHRMEN1KMT2A | |
| SCHEMBL31602884 | 0.72 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRSMN1; SMN2MEN1 | |
| SCHEMBL23536533 | 0.71 | HTR6 (0.40) | KDM4EMEN1KMT2AL3MBTL1LMNA | |
| SCHEMBL23536550 | 0.71 | HTR6 (0.34) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL23536839 | 0.68 | HSD17B10 (0.39) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL1544929 | 0.67 | HTR6 (0.56) | HTR6 | |
| SCHEMBL23536666 | 0.66 | GPR119 (0.34) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL30611197 | 0.65 | HTR6 (0.52) | ALDH1A1KDM4EMAPTRAB9AHTR6 | |
| Hydrochloric Acid SCHEMBL26911935 | 0.65 | HTR6 (0.52) | ALDH1A1KDM4EMAPTRAB9AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |