Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 4/20 | 0.37 |
| ▸ | HTR6 | P50406 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536641 | 0.91 | HTT (0.46) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL23536583 | 0.78 | HTT (0.41) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL23570345 | 0.75 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL23536609 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL23536561 | 0.73 | RORC (0.36) | ALDH1A1MAPTHTR6 | |
| SCHEMBL9778470 | 0.70 | HTR6 (0.48) | ALDH1A1HTTSMN1; SMN2NPSR1USP2 | |
| SCHEMBL9778459 | 0.70 | MAT2A (0.56) | ALDH1A1HTTSMN1; SMN2GAAGBA1 | |
| SCHEMBL23536635 | 0.69 | HSD17B10 (0.48) | ALDH1A1MEN1KMT2ALMNAHTT | |
| SCHEMBL1544929 | 0.69 | HTR6 (0.56) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL31713541 | 0.68 | GBA1 (0.38) | ALDH1A1MAPTKMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |