Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | HTR6 | P50406 | 7/20 | 0.38 |
| ▸ | RORC | P51449 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23536607 | 0.76 | HTR6 (0.44) | CCR1HTR6LMNAHTTSMN1; SMN2 | |
| SCHEMBL23536676 | 0.75 | HTR6 (0.38) | CCR1HTR6RORCLMNATP53 | |
| SCHEMBL23536654 | 0.71 | SCN5A (0.38) | CCR1HTR6RORCLMNATP53 | |
| SCHEMBL23536574 | 0.71 | SLC6A2 (0.40) | CCR1RORC | |
| SCHEMBL23536553 | 0.69 | MAPT (0.38) | CCR1HTR6RORCLMNATP53 | |
| SCHEMBL23536663 | 0.68 | HTR6 (0.46) | CCR1HTR6RORCLMNATP53 | |
| SCHEMBL2446984 | 0.67 | RORC (0.44) | HTR6RORCLMNAGAAHTT | |
| SCHEMBL6180636 | 0.66 | HDAC3 (0.57) | HTR6RORCLMNAGAAHTT | |
| SCHEMBL18867934 | 0.66 | LMNA (0.59) | LMNATP53GAAHTTSMN1; SMN2 | |
| SCHEMBL642787 | 0.66 | LMNA (0.59) | LMNATP53GAAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |