Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23567051 | 0.81 | NPC1 (0.43) | ACHERAB9ANPC1GAASMN1; SMN2 | |
| SCHEMBL13393531 | 0.77 | NQO1 (0.37) | MEN1KMT2ANQO1PORALDH1A1 | |
| SCHEMBL23567431 | 0.76 | HSD11B1 (0.46) | ADRA1DADRA1AADRA1BNOTUMALDH1A1 | |
| SCHEMBL23567062 | 0.73 | ADRA1D (0.50) | RAB9ANPC1GAASMN1; SMN2ADRA1D | |
| SCHEMBL23566250 | 0.73 | ALDH1A1 (0.47) | RAB9ANPC1GAASMN1; SMN2ADRA1D | |
| SCHEMBL13380091 | 0.72 | LMNA (0.46) | SMN1; SMN2MEN1KMT2ANQO1POR | |
| SCHEMBL1443578 | 0.72 | NQO1 (0.41) | ADRA1DADRA1AADRA1BPTPRCNQO1 | |
| SCHEMBL10166445 | 0.70 | CHRM2 (0.38) | ACHERAB9ANPC1SMN1; SMN2ADRA1D | |
| SCHEMBL2968620 | 0.69 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BPTPRCNQO1 | |
| SCHEMBL9955370 | 0.69 | NOTUM (0.44) | ACHERAB9ANPC1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210186927-A1 | COMBINATION PRODUCT FOR THE INDUCTION AND/OR MAINTENANCE OF GENERAL ANESTHESIA | TERRAN BIOSCIENCES, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186927-A1 | COMBINATION PRODUCT FOR THE INDUCTION AND/OR MAINTENANCE OF GENERAL ANESTHESIA | OPRK1, OPRD1, GABRD | ACHE 438/4885RAB9A 3441/4885NPC1 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.