Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23601500 | 0.86 | KCNA3 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL23601618 | 0.86 | EGFR (0.34) | KDM4ENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23601230 | 0.76 | SIGMAR1 (0.41) | MAPTTP53EGFRTSHRCYP2D6 | |
| SCHEMBL23600980 | 0.73 | EGFR (0.36) | KDM4ENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23601809 | 0.73 | LMNA (0.41) | HPGDMAPTEGFRCSF1RTSHR | |
| SCHEMBL23601745 | 0.73 | ABCG2 (0.36) | EGFR | |
| SCHEMBL30961049 | 0.71 | ALOX15 (0.43) | KDM4ENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23576863 | 0.71 | ALOX15 (0.43) | KDM4ENPC1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL23601069 | 0.71 | PDE5A (0.37) | MAPTEGFR | |
| SCHEMBL23601057 | 0.71 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021130638-A1 | DIACYLGLYCEROL KINASE MODULATING COMPOUNDS | CARNA BIOSCIENCES, INC. (JP) | 2021-07-01 | — | — | WO | disclosed |