SCHEMBL23607667

SCHEMBL23607667

O=C(NCC(=O)N1CCCC1)Nc1ccc2cnccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29351507 1.00 PRMT3 (1.00) PRMT3
SCHEMBL29360234 0.84 PRMT3 (0.72) PRMT3
SCHEMBL19860085 0.76 TERT (0.64) PRMT3
SCHEMBL19860074 0.75 TERT (0.63) PRMT3
SCHEMBL2162998 0.73 IMPDH2 (1.00) PRMT3
SCHEMBL20353575 0.72 IMPDH2 (1.00) PRMT3
SCHEMBL20353462 0.71 IMPDH2 (0.78) PRMT3
SCHEMBL30579695 0.71 IMPDH2 (0.72) PRMT3
SCHEMBL24381742 0.71 PRMT3 (0.57) PRMT3
SCHEMBL20353576 0.71 IMPDH2 (0.76) PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210198669-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING MUSCULAR DISORDERS AND DYSTROPHIES, STEROID SIDE EFFECTS, AND INFLAMMATION CHILDREN'S NATIONAL MEDICAL CENTER (US) 2021-07-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210198669-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING MUSCULAR DISORDERS AND DYSTROPHIES, STEROID SIDE EFFECTS, AND INFLAMMATION TNNC1, MYOF, MBNL1 PRMT3 1237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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