SCHEMBL29351507

SCHEMBL29351507

O=C(NCC(=O)N1CCCC1)Nc1ccc2cnccc2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PRMT3 O60678 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23607667 1.00 PRMT3 (1.00) PRMT3
SCHEMBL29360234 0.84 PRMT3 (0.72) PRMT3
SCHEMBL19860085 0.76 TERT (0.64) PRMT3
SCHEMBL19860074 0.75 TERT (0.63) PRMT3
SCHEMBL2162998 0.73 IMPDH2 (1.00) PRMT3
SCHEMBL20353575 0.72 IMPDH2 (1.00) PRMT3
SCHEMBL20353462 0.71 IMPDH2 (0.78) PRMT3
SCHEMBL30579695 0.71 IMPDH2 (0.72) PRMT3
SCHEMBL24381742 0.71 PRMT3 (0.57) PRMT3
SCHEMBL20353576 0.71 IMPDH2 (0.76) PRMT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059442-A1 MODULATING PLANT RESPONSES TO STRESS AND GROWTH WITH CHEMICALS REMOTE EPIGENETICS INC. (US) 2025-03-20 — — WO claimed
CN-117599057-A Application of SGC707 in preparing antiarrhythmic drugs 大连大学 2024-02-27 — — CN claimed
CN-117599056-A Application of SGC707 in preparing anti-myocardial fibrosis medicine 大连大学 2024-02-27 — — CN claimed
US-20220144902-A1 METHOD FOR INDUCING MUSCULAR CELLS USING CELLS IN SPOT URINE NIPPON SHINYAKU CO., LTD. (JP) 2022-05-12 — — US claimed
US-20260000698-A1 SARS-COV-2 NSP14 METHYLTRANSFERASE INHIBITORS UNIV MINNESOTA (US) 2026-01-01 — — US disclosed
US-20250304585-A1 SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-10-02 — — US disclosed
US-12427192-B2 Water soluble adjuvant and composition containing same Sumitomo Pharma Co., Ltd. (JP) 2025-09-30 — — US disclosed
US-12419900-B2 Induction of synthetic lethality with epigenetic therapy THE JOHNS HOPKINS UNIVERSITY (US) 2025-09-23 — — US disclosed
US-12383608-B2 WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides Sumitomo Pharma Co., Ltd. (JP) 2025-08-12 — — US disclosed
US-20250152749-A1 ASSESSMENT OF ADVERSE EVENTS INDUCED BY ADMINISTRATION OF ANTITUMOR DRUG AND/OR IMMUNE CHECKPOINT INHIBITOR BY USING DISEASE MODEL MOUSE TOHOKU UNIVERSITY (JP) 2025-05-15 — — US disclosed
EP-4540249-A1 SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS Yeda Research and Development Co. Ltd (IL) 2025-04-23 — — EP disclosed
US-12281301-B2 Sequencing-based proteomics THE BROAD INSTITUTE, INC. (US) 2025-04-22 — — US disclosed
US-20220241409-A1 WATER SOLUBLE ADJUVANT AND COMPOSITION CONTAINING SAME Sumitomo Pharma Co., Ltd. (JP) 2022-08-04 — — US disclosed
US-20220211844-A1 WATER SOLUBLE ADJUVANT AND COMPOSITION CONTAINING SAME Sumitomo Pharma Co., Ltd. (JP) 2022-07-07 — — US disclosed
US-20220175714-A1 USE OF RIVASTIGMINE IN PREPARATION OF ANTI-RADIATION MEDICAMENT SOOCHOW UNIVERSITY (CN) 2022-06-09 — — US disclosed
US-20220144902-A1 METHOD FOR INDUCING MUSCULAR CELLS USING CELLS IN SPOT URINE NIPPON SHINYAKU CO., LTD. (JP) 2022-05-12 — — US disclosed
CN-113456818-B Application of PRMT3 protein and method for regulating HIV transcription 首都医科大学附属北京儿童医院 2022-02-22 — — CN disclosed
EP-3954382-A1 WATER SOLUBLE ADJUVANT AND COMPOSITION CONTAINING SAME Sumitomo Dainippon Pharma Co., Ltd. (JP) 2022-02-16 — — EP disclosed
EP-3949983-A1 WATER SOLUBLE ADJUVANT Sumitomo Dainippon Pharma Co., Ltd. (JP) 2022-02-09 — — EP disclosed
CN-113966326-A Water soluble adjuvants 大日本住友制药株式会社 2022-01-21 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12419900-B2 Induction of synthetic lethality with epigenetic therapy MCL1, BAD, ACIN1 PRMT3 84/4885
US-12383608-B2 WT1 helper peptides and combinations of WT1 helper peptide and conjugate of cancer antigen peptides KLK3, TAP1, KLHL6 PRMT3 3266/4885
US-20220241409-A1 WATER SOLUBLE ADJUVANT AND COMPOSITION CONTAINING SAME TP53, MYD88, AQP1 PRMT3 4391/4885
US-12427192-B2 Water soluble adjuvant and composition containing same TP53, MYD88, AQP1 PRMT3 4391/4885
US-20250304585-A1 SULFAMATE BASED COVALENT LIGAND-DIRECTED RELEASE (COLDR) COMPOUNDS CASR, NPSR1, GSR PRMT3 3425/4885
US-20220211844-A1 WATER SOLUBLE ADJUVANT AND COMPOSITION CONTAINING SAME TP53, MYD88, AQP1 PRMT3 4391/4885
US-20260000698-A1 SARS-COV-2 NSP14 METHYLTRANSFERASE INHIBITORS NSUN2, SARS1, RNMT PRMT3 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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