SCHEMBL23608115

SCHEMBL23608115

[2H]COc1ccc2c(c1)c(CCN)c(C)n2C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.46
HTR6 P50406 3/20 0.43
HTR1D P28221 1/20 0.43
HTT P42858 2/20 0.42
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.40
PLA2G2A P14555 3/20 0.39
NQO2 P16083 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
BCHE P06276 2/20 0.38
ACHE P22303 2/20 0.38
SPR P35270 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23608109 0.92 ADRB2 (0.46) ADRB2HTR6HTR1DHTTHSD17B10
SCHEMBL2701682 0.90 ADRB2 (0.56) ADRB2HTR6HTR1DHTTHSD17B10
Fumaric Acid SCHEMBL23608110 0.82 PLA2G2A (0.42) ADRB2HTTALDH1A1KDM4EMEN1
SCHEMBL23777834 0.79 POLB (0.62) ADRB2HTTHSD17B10ALDH1A1KDM4E
SCHEMBL10771285 0.77 PLA2G4A (0.40) ADRB2HSD17B10ALDH1A1KDM4EMAPT
SCHEMBL18927402 0.76 KDM4E (0.53) HTTHSD17B10ALDH1A1KDM4EMEN1
SCHEMBL25416151 0.76 CYP1A2 (0.58) ADRB2HTR6HTR1DHSD17B10ALDH1A1
SCHEMBL29206563 0.76 HTR2A (0.41) HTR6MEN1KMT2ASPRCYP1A2
SCHEMBL2999508 0.76 SPR (0.39) ADRB2HTR6HTR1DHTTHSD17B10
SCHEMBL4658499 0.76 SPR (0.56) HTR6HTR1DHTTHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250042852-A1 COMPOUNDS CYBIN UK LTD (GB) 2025-02-06 US disclosed
EP-3873883-A1 METHOD OF SYNTHESIS Small Pharma Ltd (GB) 2021-09-08 EP disclosed
EP-3844147-A1 COMPOUNDS Small Pharma Ltd (GB) 2021-07-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042852-A1 COMPOUNDS DBH, ATP6V1B2, CYP11B2 ADRB2 838/4885HTR6 860/4885HTR1D 223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.