Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10771285 | 0.83 | PLA2G4A (0.40) | SPRCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL2999508 | 0.81 | SPR (0.39) | SPRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL29206563 | 0.81 | HTR2A (0.41) | SPRCYP1A2CYP3A4CYP2D6HTR6 | |
| SCHEMBL11252321 | 0.81 | SPR (0.53) | SPRBCHEACHEPLA2G2AGAA | |
| SCHEMBL18509545 | 0.81 | SPR (0.59) | SPRHSD17B10BCHEACHEPLA2G2A | |
| SCHEMBL25416151 | 0.79 | CYP1A2 (0.58) | SPRCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL2701682 | 0.79 | ADRB2 (0.56) | SPRCYP1A2CYP2D6HTR1DHTR7 | |
| SCHEMBL12721348 | 0.79 | SPR (0.54) | SPRBCHEACHEPLA2G2APTGS1 | |
| SCHEMBL335711 | 0.77 | GPR3 (0.52) | CYP2C19HSD17B10TDP1NPSR1GAA | |
| SCHEMBL23777834 | 0.76 | POLB (0.62) | SPRCYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001877-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | Bioniqs Limited (GB) | 2008-12-17 | — | — | EP | claimed |
| WO-2007110637-A1 | METHOD FOR EXTRACTING TARGET ALKALOID USING AN IONIC LIQUID AS EXTRACTING SOLVENT | BIONIQS LIMITED (GB) | 2007-10-04 | — | — | WO | claimed |
| CN-1938018-A | Use of compounds capable of increasing serum IGF-1 levels for the preparation of therapeutic compositions for the treatment of various disease states associated with decreased IGF-1 serum levels in humans and animals | VEIJLEN LTD (AN) | 2007-03-28 | — | — | CN | claimed |
| CN-116814668-A | Biosynthesis method of N-methyl serotonin and N-N-dimethyl serotonin | 福建师范大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-116761599-A | Deuterated or partially deuterated N, N-dimethyltryptamine compounds | 斯玛尔药物有限公司 | 2023-09-15 | — | — | CN | disclosed |
| CN-113968810-B | Preparation method of N, N-dimethyl-5-hydroxytryptamine | 河北维达康生物科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| US-20230149293-A1 | INJECTABLE AND INHALABLE FORMULATIONS | CYBIN UK LTD (GB) | 2023-05-18 | — | — | US | disclosed |
| CN-107018997-B | A method of fly spray is prepared using fly agaric | Yanbian Dekang Biological Technology Co., Ltd. (CN) | 2019-10-29 | — | — | CN | disclosed |
| US-20160031812-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | SOLACE PHARMACEUTICALS UK LTD. (GB) | 2016-02-04 | — | — | US | disclosed |
| US-20160031812-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | SOLACE PHARMACEUTICALS UK LTD. (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9169234-B2 | Sepiapterin reductase inhibitors for the treatment of pain | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169234-B2 | Sepiapterin reductase inhibitors for the treatment of pain | CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-20120322800-A1 | Sepiapterin Reductase Inhibitors For The Treatment of Pain | SOLACE PHARMACEUTICALS UK LTD. (GB) | 2012-12-20 | — | — | US | disclosed |
| US-20120322800-A1 | Sepiapterin Reductase Inhibitors For The Treatment of Pain | SOLACE PHARMACEUTICALS UK LTD. (GB) | 2012-12-20 | — | — | US | disclosed |
| WO-2011047156-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | HERCULES TECHNOLOGY MANAGEMENT CO V, INC. (US) | 2011-04-21 | — | — | WO | disclosed |
| CN-1938018-B | Use of compounds for the preparation of compositions for the treatment of various disease states in humans and animals associated with reduced IGF-1 serum levels | VEIJLEN LTD | 2010-09-01 | — | — | CN | disclosed |
| CN-1938018-A | Use of compounds capable of increasing serum IGF-1 levels for the preparation of therapeutic compositions for the treatment of various disease states associated with decreased IGF-1 serum levels in humans and animals | VEIJLEN LTD (AN) | 2007-03-28 | — | — | CN | disclosed |
| CN-1870992-A | Animal feed composition | VEIJLEN N V (AN) | 2006-11-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031812-A1 | SEPIAPTERIN REDUCTASE INHIBITORS FOR THE TREATMENT OF PAIN | SPR, QDPR, SRR | SPR 1/4885CYP1A2 444/4885CYP3A4 258/4885 |
| US-20120322800-A1 | Sepiapterin Reductase Inhibitors For The Treatment of Pain | SPR, QDPR, SRR | SPR 1/4885CYP1A2 444/4885CYP3A4 258/4885 |
| US-20230149293-A1 | INJECTABLE AND INHALABLE FORMULATIONS | HTR5A, HTR1B, HTR2B | SPR 3558/4885CYP1A2 1346/4885CYP3A4 1921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.