Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26010471 | 0.88 | ALDH1A1 (0.37) | PRMT5WDR77SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL23106220 | 0.88 | ALDH1A1 (0.37) | PRMT5WDR77SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL24002371 | 0.87 | ALDH1A1 (0.37) | SMN1; SMN2KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL14611470 | 0.84 | PARP1 (0.37) | PARP1KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL21575565 | 0.84 | KMT2A (0.43) | PARP1KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL26167941 | 0.83 | MAOB (0.41) | SMN1; SMN2KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL26319090 | 0.80 | MAOB (0.40) | SMN1; SMN2KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL22327196 | 0.80 | ALDH1A1 (0.36) | PRMT5WDR77SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26167764 | 0.80 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMEN1TAAR1ALDH1A1 | |
| SCHEMBL24370727 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2KMT2AMEN1TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210206794-A1 | REVERSIBLY BLOCKED NUCLEOSIDE ANALOGUES AND THEIR USE | MGI TECH CO., LTD. (CN) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210206794-A1 | REVERSIBLY BLOCKED NUCLEOSIDE ANALOGUES AND THEIR USE | NSUN2, NME2, ADAR | FURIN 1459/4885PRMT5 1871/4885WDR77 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.