Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2362223 | 0.94 | KMT2A (0.34) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL2354268 | 0.88 | KMT2A (0.38) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| Bicarbonate SCHEMBL2362868 | 0.79 | JMJD6 (0.37) | KMT2AKCNH2MGLL | |
| SCHEMBL174430 | 0.79 | PRMT6 (0.41) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL28247297 | 0.77 | PRMT6 (0.40) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL3120354 | 0.76 | KMT2A (0.35) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL1086131 | 0.75 | KMT2A (0.38) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL24050952 | 0.72 | KMT2A (0.35) | KMT2AKEAP1SCN4AKCNH2LRRK2 | |
| SCHEMBL440932 | 0.72 | KMT2A (0.41) | KMT2AKEAP1SCN4A | |
| SCHEMBL22932511 | 0.71 | KMT2A (0.38) | KMT2AKEAP1SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103044331-B | Prepare the new method of the formamide of 3 n-propyl pyrazoles of silaenafil intermediate 4 amino, 1 methyl 5 | 常州市亚邦医药研究所有限公司 | 2017-09-15 | — | — | CN | disclosed |
| EP-2352723-B1 | PESTICIDAL N-ARYL- OR N-HETEROARYL PYRAZOLE CARBOXAMIDE COMPOUNDS | BAYER IP GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| US-20150099766-A1 | Novel halogen-substituted compounds | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-09 | — | — | US | disclosed |
| US-8946234-B2 | Halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8202877-B2 | Aminopyrimidinamides as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-19 | — | — | US | disclosed |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | BAYER CROPSCIENCE AG (DE) | 2012-03-22 | — | — | US | disclosed |
| US-20110301181-A1 | halogen-substituted compounds | BAYER CROPSCIENCE AG (DE) | 2011-12-08 | — | — | US | disclosed |
| EP-2352723-A2 | HALOGEN-SUBSTITUTED COMPOUNDS USED AS PESTICIDES | Bayer CropScience AG (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (US) | 2010-11-25 | — | — | US | disclosed |
| WO-2010051926-A2 | NEW HALOGEN-SUBSTITUTED BONDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2010-05-14 | — | — | WO | disclosed |
| EP-2184273-A1 | Halogen substituted compounds as pesticides | Bayer CropScience AG (DE) | 2010-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298267-A1 | AMINOPYRIMIDINAMIDES AS PESTICIDES | DDT, NPEPPS, PTMS | KMT2A 1755/4885KEAP1 1185/4885SCN4A 1109/4885 |
| US-20110301181-A1 | halogen-substituted compounds | L3MBTL4, QSOX1, L3MBTL3 | KMT2A 1177/4885KEAP1 32/4885SCN4A 757/4885 |
| US-20120071496-A1 | Aminopyrimidinamides As Pest Control Agents | NPEPPS, DDT, DNPEP | KMT2A 785/4885KEAP1 657/4885SCN4A 1315/4885 |
| US-20150099766-A1 | Novel halogen-substituted compounds | L3MBTL4, PRDX4, PRDX1 | KMT2A 1127/4885KEAP1 29/4885SCN4A 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.