Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.37 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 3/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.32 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.32 |
| ▸ | FAP | Q12884 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23628847 | 0.73 | LMNA (0.36) | CTSLCTSSCTSK | |
| SCHEMBL2269305 | 0.68 | LOXL2 (0.43) | DPP4MMEMAOBTRPA1DPP7 | |
| SCHEMBL2268274 | 0.68 | LOXL2 (0.43) | DPP4MMEMAOBTRPA1DPP7 | |
| SCHEMBL4011260 | 0.68 | TRPA1 (0.41) | MMEMAOBACETRPA1 | |
| SCHEMBL12809801 | 0.68 | LOXL2 (0.43) | DPP4MMEMAOBTRPA1DPP7 | |
| SCHEMBL4073531 | 0.67 | LMNA (0.39) | — | |
| SCHEMBL8693276 | 0.67 | TRPA1 (0.44) | MAOBMAOATRPA1 | |
| SCHEMBL13258407 | 0.67 | CTSS (0.35) | DPP4MAOBACEMAOATRPA1 | |
| SCHEMBL29144750 | 0.67 | MAPT (0.38) | MME | |
| SCHEMBL15141781 | 0.66 | PPARG (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3846793-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2021-07-14 | — | — | EP | disclosed |