Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 3/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 2/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | GABRP | O00591 | 1/20 | 0.30 |
| ▸ | GABRD | O14764 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15666822 | 0.75 | ALDH1A1 (0.32) | RXRARXRBRXRGALDH1A1CYP3A4 | |
| SCHEMBL3021266 | 0.70 | RXRA (0.35) | RXRARXRBRXRGALDH1A1TSHR | |
| SCHEMBL6576709 | 0.70 | CYP2A6 (0.38) | ALDH1A1HPGDTSHR | |
| SCHEMBL8531806 | 0.69 | CYP1B1 (0.40) | RXRAALDH1A1CYP3A4 | |
| SCHEMBL9067362 | 0.68 | ALOX5 (0.43) | TSHRNOTUM | |
| SCHEMBL1966362 | 0.67 | NOTUM (0.33) | NOTUM | |
| SCHEMBL10570766 | 0.67 | HPGD (0.35) | ALDH1A1HPGDALOX15TDP1 | |
| SCHEMBL9539339 | 0.67 | RORB (0.46) | ALDH1A1CYP3A4HPGDTSHRHIF1A | |
| SCHEMBL8798556 | 0.66 | ALDH1A1 (0.40) | ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL8190384 | 0.66 | CYP2A6 (0.38) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9456605-B2 | Isoxazoline derivatives as insecticides | SYNGENTA CROP PROTECTION, LLC (US) | 2016-10-04 | — | — | US | disclosed |
| US-20140249316-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2014-09-04 | — | — | US | disclosed |
| WO-2011101402-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249316-A1 | ISOXAZOLINE DERIVATIVES AS INSECTICIDES | ACHE, CHRM1, ITPR3 | RXRA 1633/4885RXRB 1811/4885RXRG 2200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.