Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237713 | 0.82 | RAB9A (0.54) | HPGDALDH1A1RAB9AKDM4EHDAC1 | |
| SCHEMBL4881536 | 0.80 | HPGD (0.57) | HPGDALDH1A1RAB9AKDM4EHDAC1 | |
| SCHEMBL10569530 | 0.78 | ALDH1A1 (0.55) | HPGDALDH1A1RAB9AHDAC1CTSL | |
| SCHEMBL1605401 | 0.78 | ALDH1A1 (0.55) | HPGDALDH1A1RAB9AHDAC1CTSL | |
| Methylamine SCHEMBL10771739 | 0.76 | HPGD (0.53) | HPGDALDH1A1RAB9AHDAC1CYP1A2 | |
| SCHEMBL8144689 | 0.76 | KDM4E (0.78) | HPGDALDH1A1RAB9AKDM4EHDAC1 | |
| SCHEMBL2364024 | 0.75 | CYP1A2 (0.55) | ALDH1A1KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL2364158 | 0.75 | HSPA9 (0.42) | ALDH1A1HDAC1 | |
| SCHEMBL9829545 | 0.75 | KDM4E (0.76) | HPGDALDH1A1RAB9AKDM4EHDAC1 | |
| SCHEMBL9830587 | 0.74 | KDM4E (0.73) | HPGDALDH1A1RAB9AKDM4EHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095218-A1 | TEMPLATE-FIXED PEP TIDOMIME TICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |