Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364635 | 0.88 | KMT2A (0.49) | KMT2AMEN1GAAALDH1A1GLA | |
| SCHEMBL2365010 | 0.77 | L3MBTL1 (0.50) | KMT2AMEN1GAAALDH1A1RAB9A | |
| SCHEMBL2364807 | 0.75 | ALDH1A1 (0.37) | KMT2AMEN1GAAALDH1A1HPGD | |
| SCHEMBL2364868 | 0.74 | KMT2A (0.38) | KMT2AMEN1GAAALDH1A1KDM4E | |
| SCHEMBL2364652 | 0.73 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL29023278 | 0.71 | KMT2A (0.39) | KMT2AMEN1GAAALDH1A1CA12 | |
| SCHEMBL9829583 | 0.70 | CXCR2 (0.42) | KMT2AALDH1A1HIF1A | |
| SCHEMBL9829581 | 0.70 | CXCR2 (0.42) | KMT2AALDH1A1HIF1A | |
| SCHEMBL20153912 | 0.69 | SMN1; SMN2 (0.46) | NFE2L2KMT2AMEN1GAACA12 | |
| SCHEMBL27406262 | 0.69 | ALDH1A1 (0.39) | KMT2AALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |