Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.34 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9594918 | 0.78 | ALDH1A1 (0.40) | ALDH1A1RECQLTRPA1ATMTDP1 | |
| SCHEMBL2364868 | 0.78 | KMT2A (0.38) | ALDH1A1RECQLMEN1KMT2ALMNA | |
| SCHEMBL2364652 | 0.78 | ALDH1A1 (0.38) | ALDH1A1RECQLMEN1KMT2ALMNA | |
| SCHEMBL9595432 | 0.77 | POLB (0.39) | ALDH1A1RECQLTRPA1ATMTDP1 | |
| SCHEMBL2364635 | 0.75 | KMT2A (0.49) | ALDH1A1RECQLATMMEN1KMT2A | |
| SCHEMBL2364591 | 0.75 | NFE2L2 (0.41) | ALDH1A1ATMMEN1KMT2APOLB | |
| SCHEMBL9829583 | 0.74 | CXCR2 (0.42) | ALDH1A1RECQLCYP1A2KMT2ALMNA | |
| SCHEMBL28812067 | 0.74 | TRPA1 (0.41) | ALDH1A1TRPA1ATMTDP1MEN1 | |
| SCHEMBL9829581 | 0.74 | CXCR2 (0.42) | ALDH1A1RECQLCYP1A2KMT2ALMNA | |
| SCHEMBL2365010 | 0.73 | L3MBTL1 (0.50) | ALDH1A1RECQLATMTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |