Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364591 | 0.88 | NFE2L2 (0.41) | KMT2AMEN1ATMALDH1A1GAA | |
| SCHEMBL2365010 | 0.86 | L3MBTL1 (0.50) | KMT2AMEN1ATMALDH1A1GAA | |
| SCHEMBL2364652 | 0.79 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL9829581 | 0.77 | CXCR2 (0.42) | KMT2AALDH1A1MAPTRECQLLMNA | |
| SCHEMBL9829583 | 0.77 | CXCR2 (0.42) | KMT2AALDH1A1MAPTRECQLLMNA | |
| SCHEMBL2364807 | 0.75 | ALDH1A1 (0.37) | KMT2AMEN1ATMALDH1A1GAA | |
| SCHEMBL29675910 | 0.75 | KMT2A (0.49) | KMT2AMEN1ATMALDH1A1MTNR1A | |
| SCHEMBL2364868 | 0.74 | KMT2A (0.38) | KMT2AMEN1ALDH1A1GAAPOLB | |
| SCHEMBL27403148 | 0.73 | ALDH1A1 (0.41) | KMT2AMEN1ATMALDH1A1MTNR1A | |
| SCHEMBL8615774 | 0.73 | KDM4E (0.38) | KMT2AMEN1ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |