Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2364635 | 0.86 | KMT2A (0.49) | POLBATMMEN1KMT2AGAA | |
| SCHEMBL2364591 | 0.77 | NFE2L2 (0.41) | POLBATMMEN1KMT2AGAA | |
| SCHEMBL2364652 | 0.77 | ALDH1A1 (0.38) | POLBMEN1KMT2AADRA2CLMNA | |
| SCHEMBL9829581 | 0.75 | CXCR2 (0.42) | L3MBTL1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL9829583 | 0.75 | CXCR2 (0.42) | L3MBTL1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL2364807 | 0.73 | ALDH1A1 (0.37) | POLBATMMEN1KMT2AGAA | |
| SCHEMBL3745836 | 0.73 | L3MBTL1 (0.50) | L3MBTL1NPSR1POLBATMTSPO | |
| SCHEMBL2364868 | 0.72 | KMT2A (0.38) | L3MBTL1POLBMEN1KMT2AGAA | |
| SCHEMBL12585668 | 0.71 | CTNNB1 (0.47) | L3MBTL1NPSR1POLBATMTSPO | |
| SCHEMBL9482735 | 0.70 | L3MBTL1 (0.50) | L3MBTL1NPSR1POLBATMTSPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |