SCHEMBL23646249

SCHEMBL23646249

O=C(O)CCCCCCCCCCCCCNC(=O)CN1CCC(O)(C(F)(F)F)CC1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.41
ADRA1A P35348 1/20 0.39
ALDH1A1 P00352 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
HDAC3 O15379 1/20 0.37
EPHX2 P34913 5/20 0.36
ALOX5 P09917 1/20 0.36
FOLH1 Q04609 1/20 0.36
MAPK1 P28482 1/20 0.35
SIGMAR1 Q99720 2/20 0.35
EPHX1 P07099 1/20 0.35
PLA2G2A P14555 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23646284 0.84 PRMT1 (0.45) PRMT1ADRA1AALDH1A1SMN1; SMN2HDAC3
SCHEMBL23646236 0.82 ITGB3 (0.48) PRMT1ADRA1AEPHX2ALOX5MAPK1
SCHEMBL23646279 0.82 ITGB3 (0.48) PRMT1ADRA1AEPHX2ALOX5MAPK1
SCHEMBL23646286 0.82 ITGB3 (0.48) PRMT1ADRA1AEPHX2ALOX5MAPK1
SCHEMBL23646277 0.82 ITGB3 (0.48) PRMT1ADRA1AEPHX2ALOX5MAPK1
SCHEMBL23646230 0.78 ALDH1A1 (0.35) PRMT1ADRA1AALDH1A1SMN1; SMN2EPHX2
SCHEMBL20385914 0.75 ADRA1A (0.49) PRMT1ADRA1AALDH1A1SMN1; SMN2EPHX2
SCHEMBL5204373 0.73 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2FOLH1SIGMAR1
SCHEMBL6014048 0.72 ADRA1A (0.42) PRMT1ADRA1AALDH1A1SMN1; SMN2EPHX2
SCHEMBL25575666 0.72 ADRA1A (0.42) PRMT1ADRA1AALDH1A1SMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12258324-B2 Fatty acid analogues and methods of use LIN BIOSCIENCE INC. (TW) 2025-03-25 US disclosed
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE LIN BIOSCIENCE INC. (TW) 2021-07-22 US disclosed
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE LIN BIOSCIENCE INC. (TW) 2021-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210221781-A1 FATTY ACID ANALOGUES AND METHODS OF USE ELOVL1, FADS1, ALOX5 PRMT1 4275/4885ADRA1A 1498/4885ALDH1A1 1214/4885
US-12258324-B2 Fatty acid analogues and methods of use ELOVL1, FADS1, ALOX5 PRMT1 4275/4885ADRA1A 1498/4885ALDH1A1 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.