Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | ADH1B | P00325 | 1/20 | 0.46 |
| ▸ | ADH1C | P00326 | 1/20 | 0.46 |
| ▸ | ADH1A | P07327 | 1/20 | 0.46 |
| ▸ | ADH7 | P40394 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23655611 | 0.95 | NCF1 (0.51) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655578 | 0.86 | CA2 (0.43) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655548 | 0.86 | GAA (0.44) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655342 | 0.85 | ADH1B (0.61) | MAPTGAAALDH1A1LMNAALOX15 | |
| SCHEMBL31566 | 0.84 | ADH1B (0.61) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655583 | 0.84 | ADH1B (0.46) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655787 | 0.84 | L3MBTL1 (0.53) | MAPTGAAALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL3305094 | 0.83 | ALDH1A1 (0.53) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23655375 | 0.83 | RAB9A (0.56) | MAPTGAASMN1; SMN2LMNANPC1 | |
| SCHEMBL3304463 | 0.82 | L3MBTL1 (0.54) | MAPTGAAKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3027615-B1 | ANTI-INFECTIVE COMPOUNDS | PASTEUR INSTITUT KOREA (KR) | 2021-07-21 | — | — | EP | disclosed |