SCHEMBL23655583

SCHEMBL23655583

O=CNCc1ccc(N2CCN(c3ccc(P)cc3)CC2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.46
ADH1C P00326 1/20 0.46
ADH1A P07327 1/20 0.46
ADH7 P40394 1/20 0.46
NCF1 P14598 1/20 0.41
GAA P10253 6/20 0.38
MAPT P10636 4/20 0.38
ALOX15 P16050 4/20 0.38
ALOX12 P18054 4/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
GFER P55789 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23655342 0.85 ADH1B (0.61) ADH1BADH1CADH1AADH7GAA
SCHEMBL23655787 0.84 L3MBTL1 (0.53) ADH1BADH1CADH1AADH7GAA
SCHEMBL23655331 0.84 MAPT (0.53) ADH1BADH1CADH1AADH7NCF1
SCHEMBL3305094 0.83 ALDH1A1 (0.53) ADH1BADH1CADH1AADH7NCF1
SCHEMBL23655809 0.82 CYP2C9 (0.36) ADH1BADH1CADH1AADH7NCF1
SCHEMBL3304463 0.82 L3MBTL1 (0.54) ADH1BADH1CADH1AADH7GAA
SCHEMBL24677480 0.81 ADRB1 (0.47) ADH1BADH1CADH1AADH7NCF1
SCHEMBL23655611 0.80 NCF1 (0.51) ADH1BADH1CADH1AADH7NCF1
SCHEMBL23655375 0.80 RAB9A (0.56) GAAMAPTGFERSMN1; SMN2L3MBTL1
SCHEMBL23655531 0.78 SMN1; SMN2 (0.49) ADH1BADH1CADH1AADH7NCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3027615-B1 ANTI-INFECTIVE COMPOUNDS PASTEUR INSTITUT KOREA (KR) 2021-07-21 EP disclosed