Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 3/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365755 | 0.86 | PPARG (0.41) | PPARGKMT2AFAAHCNR2MEN1 | |
| SCHEMBL2365612 | 0.85 | HSD11B1 (0.47) | IP6K1IP6K3IP6K2PPARGHSD11B1 | |
| SCHEMBL2365642 | 0.77 | FAAH (0.52) | FAAHCYP2C9MAPK1HSD11B1 | |
| SCHEMBL2365656 | 0.76 | P2RX7 (0.39) | KMT2AMEN1TSHRSMN1; SMN2GRM5 | |
| SCHEMBL13366027 | 0.75 | NR1H2 (0.53) | IP6K1IP6K3IP6K2PPARGCCR2 | |
| SCHEMBL2365727 | 0.74 | P2RX7 (0.37) | KMT2AFAAHMEN1TSHRSMN1; SMN2 | |
| SCHEMBL2365611 | 0.74 | PPARG (0.63) | IP6K1IP6K3IP6K2PPARGCCR2 | |
| SCHEMBL1675961 | 0.72 | FAAH (0.55) | KMT2AFAAHCNR2MEN1P2RX7 | |
| SCHEMBL1168572 | 0.72 | HSD11B1 (0.48) | HSD11B1 | |
| SCHEMBL2365692 | 0.71 | L3MBTL1 (0.56) | IP6K1IP6K3IP6K2PPARGCCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362730-A1 | ADAMANTYL BENZAMIDE COMPOUNDS | High Point Pharmaceuticals, LLC (US) | 2011-09-07 | — | — | EP | disclosed |
| WO-2010059618-A1 | ADAMANTYL BENZAMIDE COMPOUNDS | HIGH POINT PHARMACEUTICALS, LLC (US) | 2010-05-27 | — | — | WO | disclosed |