Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | IL1RN | P18510 | 2/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2367197 | 1.00 | CTSS (0.44) | CTSSCTSLCTSKATMIL1RN | |
| SCHEMBL2367498 | 0.90 | CTSS (0.46) | CTSSCTSLCTSKATMIL1RN | |
| SCHEMBL2367398 | 0.85 | CTSS (0.44) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL2367415 | 0.85 | CTSS (0.44) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL2367512 | 0.84 | CTSL (0.41) | CTSSCTSLCTSKIL1RNERAP2 | |
| SCHEMBL2367196 | 0.84 | CTSC (0.45) | CTSSCTSLCTSKMMEANPEP | |
| SCHEMBL2367824 | 0.83 | CTSK (0.43) | CTSSCTSLCTSKCTSB | |
| SCHEMBL12292722 | 0.83 | ALDH1A1 (0.48) | CTSSCTSLCTSKATMIL1RN | |
| SCHEMBL12292724 | 0.83 | ALDH1A1 (0.48) | CTSSCTSLCTSKATMIL1RN | |
| SCHEMBL2367378 | 0.83 | PSMB1 (0.41) | CTSSCTSLCTSKMMEANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |