Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ASPH | Q12797 | 1/20 | 0.31 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30866576 | 0.76 | DHODH (0.37) | KDM4EASPHKDM8 | |
| SCHEMBL30459905 | 0.67 | MAP2K1 (0.35) | KDM4E | |
| SCHEMBL23673990 | 0.67 | MAP2K1 (0.35) | KDM4E | |
| SCHEMBL27224628 | 0.66 | MAP2K1 (0.38) | KDM4EASPHKDM8 | |
| SCHEMBL8932122 | 0.65 | KDM4E (0.43) | KDM4EASPHKDM8 | |
| SCHEMBL28710108 | 0.61 | ALDH1A1 (0.41) | KDM4CALDH1A1KDM4EASPHKDM8 | |
| SCHEMBL9455801 | 0.61 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8932031 | 0.60 | ACHE (0.40) | — | |
| SCHEMBL24770298 | 0.60 | DHODH (0.42) | — | |
| SCHEMBL27224638 | 0.60 | DHODH (0.37) | KDM4EASPHKDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021149776-A1 | ARYLAMIDE DERIVATIVE HAVING ANTITUMOR ACTIVITY | 中外製薬株式会社 | 2021-07-29 | — | — | WO | disclosed |