Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358684 | 0.84 | LMNA (0.40) | ALDH1A1ALOX15MAPK1HSD17B10TSHR | |
| SCHEMBL30341175 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TSHRLMNASMN1; SMN2DAPK3 | |
| SCHEMBL30341183 | 0.78 | NPC1 (0.47) | ALDH1A1MAPK1LMNASMN1; SMN2DAPK3 | |
| SCHEMBL2368300 | 0.76 | ESR1 (0.47) | ALDH1A1MAPK1HSD17B10TSHRLMNA | |
| SCHEMBL14965210 | 0.76 | ADORA1 (0.50) | ALDH1A1LMNASMN1; SMN2DAPK3PRKD3 | |
| SCHEMBL6356763 | 0.76 | SQOR (0.37) | ALDH1A1ALOX15MAPK1HSD17B10TSHR | |
| SCHEMBL2369195 | 0.76 | DAPK3 (0.40) | ALDH1A1ALOX15MAPK1HSD17B10TSHR | |
| SCHEMBL2368984 | 0.76 | FGFR1 (0.41) | ALDH1A1MAPK1HSD17B10TSHRLMNA | |
| SCHEMBL2368787 | 0.75 | CYP1A2 (0.42) | ALDH1A1MAPK1HSD17B10TSHRDAPK3 | |
| SCHEMBL6359795 | 0.74 | ALDH1A1 (0.42) | ALDH1A1ALOX15MAPK1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022076-B2 | Thieno[2,3-d]pyrimidine derivatives as potassium channel modulators; antiarrhythmia agents | XENTION LIMITED (GB) | 2011-09-20 | — | — | US | disclosed |