Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368935 | 0.84 | ALDH1A1 (0.44) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL30341175 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL31248556 | 0.76 | LMNA (0.52) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30341183 | 0.74 | NPC1 (0.47) | LMNAALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL2368300 | 0.73 | ESR1 (0.47) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL14965210 | 0.73 | ADORA1 (0.50) | LMNAALDH1A1KMT2ASMN1; SMN2DAPK3 | |
| SCHEMBL6356763 | 0.73 | SQOR (0.37) | LMNAALDH1A1KDM4ETSHRMAPK1 | |
| SCHEMBL2368984 | 0.72 | FGFR1 (0.41) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2369195 | 0.72 | DAPK3 (0.40) | LMNAALDH1A1KDM4ESMN1; SMN2TSHR | |
| SCHEMBL2368787 | 0.72 | CYP1A2 (0.42) | ALDH1A1KDM4ETDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050026935-A1 | Compounds | XENTION DISCOVERY LTD. | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050026935-A1 | Compounds | KCNJ11, KCNJ1, KCNH1 | LMNA 1126/4885ALDH1A1 247/4885KDM4E 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.