SCHEMBL6356763

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2368984	0.85	FGFR1 (0.41)	PRNPTSHRCCNCCDK8FGFR1
	SCHEMBL2368787	0.81	CYP1A2 (0.42)	SQORTSHRFGFR1DAPK3PRKD3
	SCHEMBL2368935	0.76	ALDH1A1 (0.44)	TSHRFGFR1DAPK3PRKD3MAP4K4
	SCHEMBL30341175	0.74	ALDH1A1 (0.46)	TSHRFGFR1DAPK3PRKD3MAP4K4
	SCHEMBL6358684	0.73	LMNA (0.40)	TSHRFGFR1DAPK3PRKD3MAP4K4
	SCHEMBL30341183	0.72	NPC1 (0.47)	FGFR1DAPK3PRKD3MAP4K4ABL1
	SCHEMBL2368980	0.71	LMNA (0.40)	PRNPTSHRCCNCCDK8FGFR1
	SCHEMBL14965210	0.71	ADORA1 (0.50)	FGFR1DAPK3PRKD3MAP4K4ABL1
	SCHEMBL2368300	0.71	ESR1 (0.47)	TSHRFGFR1DAPK3PRKD3MAP4K4
	SCHEMBL2369195	0.71	DAPK3 (0.40)	TSHRFGFR1DAPK3PRKD3MAP4K4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.