Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | FBP1 | P09467 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23700602 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL16627248 | 0.83 | NPC1 (0.47) | ALDH1A1HPGDFBP1HSD17B10MAPT | |
| SCHEMBL10351098 | 0.74 | ALDH1A1 (0.72) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL26964585 | 0.74 | ALDH1A1 (0.58) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL9306312 | 0.73 | POLB (0.56) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL16625024 | 0.72 | FBP1 (0.54) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL16625015 | 0.71 | NPC1 (0.50) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL9304684 | 0.71 | POLB (0.53) | ALDH1A1HPGDALOX15FBP1HSD17B10 | |
| SCHEMBL718296 | 0.71 | PPARA (0.67) | ALDH1A1HPGDALOX15HSD17B10MAPT | |
| Benzothiazyl Disulfide SCHEMBL28862975 | 0.71 | ALDH1A1 (0.67) | ALDH1A1HPGDALOX15FBP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | THE JOHNS HOPKINS UNIVERSTY | 2023-08-03 | — | — | US | disclosed |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | THE JOHNS HOPKINS UNIVERSTY | 2023-08-03 | — | — | US | disclosed |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | THE JOHNS HOPKINS UNIVERSITY (US) | 2023-02-21 | — | — | US | disclosed |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | NATIONAL SCIENCE FOUNDATION | 2021-08-05 | — | — | US | disclosed |
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | NATIONAL SCIENCE FOUNDATION | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238134-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | ALDH1A1 1063/4885HPGD 300/4885ALOX15 841/4885 |
| US-20230242479-A1 | ALKYLAMINE-SUBSTITUTED PERTHIOCARBAMATES AS DUAL PRECURSORS TO HYDROPERSULFIDE AND CARBONYL SULFIDE | CTH, DOHH, HAGH | ALDH1A1 1063/4885HPGD 300/4885ALOX15 841/4885 |
| US-11584712-B2 | Alkylamine-substituted perthiocarbamates as dual precursors to hydropersulfide and carbonyl sulfide | CTH, DOHH, HAGH | ALDH1A1 1063/4885HPGD 300/4885ALOX15 841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.