Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PFKFB4 | Q16877 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | FBP1 | P09467 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2371407 | 0.89 | MEN1 (0.54) | ALDH1A1KMT2AGAAMEN1FBP1 | |
| SCHEMBL15342920 | 0.78 | CA1 (0.52) | ALDH1A1KMT2AGAAMEN1FBP1 | |
| SCHEMBL5323412 | 0.77 | HCAR2 (0.50) | ALDH1A1PFKFB4SMN1; SMN2RAB9A | |
| SCHEMBL11893065 | 0.76 | CA1 (0.60) | ALDH1A1KMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL4200929 | 0.75 | ALDH1A1 (0.80) | ALDH1A1KMT2AGAAMEN1SMN1; SMN2 | |
| SCHEMBL3251168 | 0.75 | MAPT (0.51) | KMT2AGAAMEN1KMORECQL | |
| SCHEMBL3256497 | 0.74 | AKT1 (0.48) | ALDH1A1 | |
| SCHEMBL4256153 | 0.73 | RAB9A (0.65) | ALDH1A1PFKFB4SMN1; SMN2RAB9A | |
| SCHEMBL3154592 | 0.72 | CA1 (0.55) | KMT2AGAAMEN1SMN1; SMN2CA1 | |
| SCHEMBL14921838 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KMT2AGAAMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | TAKEDA CALIFORNIA, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | TAKEDA CALIFORNIA, INC. (US) | 2013-10-24 | — | — | US | disclosed |
| EP-2547667-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | Takeda California, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011115758-A1 | PROCESS FOR THE PRODUCTION OF 2-AMINO-5-FLUOROTHIAZOLE | TAKEDA SAN DIEGO, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281708-A1 | Process for the Production of 2-Amino-5-Fluorothiazole | GFPT1, PFAS, PFKFB4 | ALDH1A1 1653/4885PFKFB4 3/4885KMT2A 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.