SCHEMBL23701730

SCHEMBL23701730

O=C(O)Cc1c[nH]c2ccc(-c3ccc4c(c3)OCO4)cc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
LMNA P02545 2/20 0.57
CYP2C9 P11712 2/20 0.57
NPSR1 Q6W5P4 2/20 0.57
ALDH1A1 P00352 1/20 0.57
GLA P06280 1/20 0.57
HPGD P15428 1/20 0.57
NFKB1 P19838 1/20 0.57
PMP22 Q01453 1/20 0.57
KDM4E B2RXH2 1/20 0.52
HTT P42858 1/20 0.52
ICMT O60725 7/20 0.50
CNR2 P34972 1/20 0.46
NR4A1 P22736 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
USP2 O75604 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23702340 0.90 HTT (0.52) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL23701757 0.81 TSHR (0.66) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL30261856 0.81 TSHR (0.66) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL6509009 0.79 TSHR (0.62) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL5213952 0.78 ICMT (0.47) LMNACYP2C9NPSR1ALDH1A1KDM4E
SCHEMBL23701758 0.77 ICMT (0.64) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL23701735 0.77 TSHR (0.61) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL23701731 0.76 ALDH1A1 (0.59) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL17018978 0.76 HTT (0.41) TSHRLMNACYP2C9NPSR1ALDH1A1
SCHEMBL23701770 0.75 ICMT (0.79) TSHRLMNACYP2C9NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB TSHR 57/4885LMNA 4744/4885CYP2C9 3300/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB TSHR 57/4885LMNA 4744/4885CYP2C9 3300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.