SCHEMBL23701741

SCHEMBL23701741

COc1ccc(-c2ccc3[nH]cc(CC(=O)O)c3c2)cc1C

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.63
ICMT O60725 8/20 0.56
TSHR P16473 2/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
GLA P06280 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
NFKB1 P19838 1/20 0.54
PMP22 Q01453 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
SCN9A Q15858 1/20 0.45
KMT2A Q03164 1/20 0.45
PPARG P37231 1/20 0.44
PPARD Q03181 1/20 0.44
PPARA Q07869 1/20 0.44
CPT1A P50416 1/20 0.44
CPT1B Q92523 1/20 0.44
FFAR1 O14842 1/20 0.44
HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701735 0.86 TSHR (0.61) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL23701771 0.82 TSHR (0.63) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL23701762 0.82 ICMT (0.81) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL23701758 0.81 ICMT (0.64) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL22470068 0.81 KDM4E (0.74) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL29486505 0.81 KDM4E (0.74) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL30261856 0.79 TSHR (0.66) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL23701757 0.79 TSHR (0.66) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL23701770 0.79 ICMT (0.79) KDM4EICMTTSHRALDH1A1LMNA
SCHEMBL674415 0.78 KDM4E (1.00) KDM4ETSHRALDH1A1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB KDM4E 1967/4885ICMT 1658/4885TSHR 57/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB KDM4E 1967/4885ICMT 1658/4885TSHR 57/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.