Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 7/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.49 |
| ▸ | CCND1 | P24385 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23701732 | 0.89 | ICMT (0.79) | ICMTKDM4ELMNACYP2C9ALDH1A1 | |
| SCHEMBL23702342 | 0.84 | ICMT (0.58) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL12762891 | 0.84 | MAP4K1 (0.64) | ICMTKDM4E | |
| SCHEMBL23701741 | 0.82 | KDM4E (0.63) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL6923141 | 0.81 | ICMT (0.67) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL23701757 | 0.81 | TSHR (0.66) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL30261856 | 0.81 | TSHR (0.66) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL5213599 | 0.80 | ICMT (0.61) | ICMTKDM4ELMNACYP2C9ALDH1A1 | |
| SCHEMBL22470068 | 0.80 | KDM4E (0.74) | ICMTKDM4ETSHRLMNACYP2C9 | |
| SCHEMBL29486505 | 0.80 | KDM4E (0.74) | ICMTKDM4ETSHRLMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12150447-B2 | Plant growth regulator | UNIVERSITY OF WASHINGTON (US) | 2024-11-26 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
| US-20210235697-A1 | PLANT GROWTH REGULATOR | UNIVERSITY OF WASHINGTON (US) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210235697-A1 | PLANT GROWTH REGULATOR | ING2, GHRHR, MYB | ICMT 1658/4885KDM4E 1967/4885TSHR 57/4885 |
| US-12150447-B2 | Plant growth regulator | ING2, GHRHR, MYB | ICMT 1658/4885KDM4E 1967/4885TSHR 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.