SCHEMBL23701771

SCHEMBL23701771

Cc1cc(-c2ccc3[nH]cc(CC(=O)O)c3c2)ccc1F

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.63
ICMT O60725 8/20 0.58
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
GLA P06280 1/20 0.57
CYP2C9 P11712 1/20 0.57
HPGD P15428 1/20 0.57
NFKB1 P19838 1/20 0.57
PMP22 Q01453 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
KDM4E B2RXH2 1/20 0.55
NR4A1 P22736 1/20 0.45
PPARG P37231 1/20 0.43
PPARD Q03181 1/20 0.43
PPARA Q07869 1/20 0.43
MTNR1A P48039 2/20 0.43
MTNR1B P49286 2/20 0.43
NOTUM Q6P988 1/20 0.43
CNR2 P34972 1/20 0.43
RXRA P19793 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701735 0.88 TSHR (0.61) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23701729 0.85 ICMT (0.80) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23701758 0.83 ICMT (0.64) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23701741 0.82 KDM4E (0.63) TSHRICMTALDH1A1LMNAGLA
SCHEMBL6509009 0.81 TSHR (0.62) TSHRICMTALDH1A1LMNAGLA
SCHEMBL30261856 0.81 TSHR (0.66) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23701757 0.81 TSHR (0.66) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23701770 0.81 ICMT (0.79) TSHRICMTALDH1A1LMNAGLA
SCHEMBL23702342 0.80 ICMT (0.58) TSHRICMTALDH1A1LMNAGLA
SCHEMBL4436389 0.79 PPARG (0.43) TSHRICMTALDH1A1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB TSHR 57/4885ICMT 1658/4885ALDH1A1 3460/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB TSHR 57/4885ICMT 1658/4885ALDH1A1 3460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.