SCHEMBL23701799

SCHEMBL23701799

COC(=O)Cc1c[nH]c2ccc(-c3cccc(OC)c3)cc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ICMT O60725 6/20 0.62
KDM4E B2RXH2 2/20 0.58
MTNR1A P48039 4/20 0.53
MTNR1B P49286 3/20 0.53
TRPV1 Q8NER1 2/20 0.53
FAAH O00519 2/20 0.53
MEN1 O00255 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52
KMT2A Q03164 2/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
TP53 P04637 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
HIF1A Q16665 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
MMP2 P08253 1/20 0.52
MMP9 P14780 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486505 0.89 KDM4E (0.74) ICMTKDM4EMTNR1AMTNR1BTRPV1
SCHEMBL22470068 0.89 KDM4E (0.74) ICMTKDM4EMTNR1AMTNR1BTRPV1
SCHEMBL30098548 0.88 NR4A2 (0.62) ICMTKDM4ETRPV1FAAHMEN1
SCHEMBL23718989 0.88 NR4A2 (0.62) ICMTKDM4ETRPV1FAAHMEN1
SCHEMBL2686551 0.86 KDM4E (0.77) KDM4EMTNR1AMTNR1BMEN1CYP1A2
SCHEMBL23701740 0.84 ICMT (0.55) ICMTKDM4EMTNR1AMTNR1BTRPV1
SCHEMBL24445971 0.81 ICMT (0.56) ICMTKDM4EMTNR1AMTNR1BMEN1
SCHEMBL8172209 0.81 PKM (0.59) ICMTKDM4EMTNR1AMTNR1BMEN1
SCHEMBL23701732 0.80 ICMT (0.79) ICMTKDM4EMTNR1AMTNR1BTRPV1
SCHEMBL31127578 0.80 HDAC6 (0.55) ICMTKDM4EMTNR1AMTNR1BTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB ICMT 1658/4885KDM4E 1967/4885MTNR1A 334/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB ICMT 1658/4885KDM4E 1967/4885MTNR1A 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.