SCHEMBL23701740

SCHEMBL23701740

COC(=O)Cc1c[nH]c2ccc(-c3ccc4ccccc4c3)cc12

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ICMT O60725 6/20 0.55
KDM4E B2RXH2 1/20 0.50
NR4A2 P43354 1/20 0.49
PKM P14618 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
CNR2 P34972 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
TRPV1 Q8NER1 2/20 0.46
FAAH O00519 1/20 0.46
SCN9A Q15858 2/20 0.46
MTNR1A P48039 1/20 0.46
MTNR1B P49286 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30098548 0.89 NR4A2 (0.62) ICMTKDM4ENR4A2PKMMEN1
SCHEMBL23718989 0.89 NR4A2 (0.62) ICMTKDM4ENR4A2PKMMEN1
SCHEMBL23701731 0.85 ALDH1A1 (0.59) ICMTKDM4EMEN1KMT2AALDH1A1
SCHEMBL23701799 0.84 ICMT (0.62) ICMTKDM4EMEN1KMT2AALDH1A1
SCHEMBL24445971 0.82 ICMT (0.56) ICMTKDM4ENR4A2PKMMEN1
SCHEMBL23718992 0.82 ICMT (0.47) ICMTKDM4ENR4A2PKMMEN1
SCHEMBL23701732 0.81 ICMT (0.79) ICMTKDM4ENR4A2PKMMEN1
SCHEMBL2686551 0.79 KDM4E (0.77) KDM4ENR4A2MEN1KMT2AALDH1A1
SCHEMBL29466101 0.79 PKM (0.73) KDM4EPKMMEN1KMT2AALDH1A1
SCHEMBL584367 0.79 PKM (0.73) KDM4EPKMMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12150447-B2 Plant growth regulator UNIVERSITY OF WASHINGTON (US) 2024-11-26 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed
US-20210235697-A1 PLANT GROWTH REGULATOR UNIVERSITY OF WASHINGTON (US) 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210235697-A1 PLANT GROWTH REGULATOR ING2, GHRHR, MYB ICMT 1658/4885KDM4E 1967/4885NR4A2 936/4885
US-12150447-B2 Plant growth regulator ING2, GHRHR, MYB ICMT 1658/4885KDM4E 1967/4885NR4A2 936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.