Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23708148 | 0.78 | ALOX5 (0.52) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL23708081 | 0.75 | KDM4E (0.43) | ALDH1A1KDM4EL3MBTL1HPGDMAPK1 | |
| SCHEMBL23708502 | 0.75 | KEAP1 (0.56) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL23708146 | 0.73 | RARA (0.51) | ALDH1A1KDM4ELMNAL3MBTL1LTA4H | |
| SCHEMBL23707895 | 0.72 | KDM4E (0.63) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL23708106 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL23708324 | 0.71 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPK1TSHR | |
| SCHEMBL16793286 | 0.71 | AR (0.59) | ALDH1A1KDM4ELMNAL3MBTL1HPGD | |
| SCHEMBL23708171 | 0.71 | NCF1 (0.48) | ALDH1A1KDM4ELMNAL3MBTL1TSHR | |
| SCHEMBL16793323 | 0.70 | NCF1 (0.47) | ALDH1A1KDM4ELMNAL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154966-A1 | COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS | KAMARI PHARMA LTD. (IL) | 2021-08-05 | — | — | WO | disclosed |