Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | PYGL | P06737 | 9/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716193 | 0.75 | OGG1 (0.44) | KMT2A | |
| SCHEMBL23716330 | 0.73 | MDM2 (0.38) | MEN1NPC1KMT2A | |
| SCHEMBL23716135 | 0.70 | KMT2A (0.37) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL23715916 | 0.68 | OGG1 (0.44) | — | |
| SCHEMBL3412727 | 0.67 | F7 (0.58) | SIRT1F7F3PYGLFLT3 | |
| SCHEMBL23716111 | 0.66 | OGG1 (0.45) | — | |
| SCHEMBL764543 | 0.63 | F7 (0.72) | SIRT1F7F3PYGLFLT3 | |
| SCHEMBL28037962 | 0.63 | F7 (0.49) | SIRT1F7F3PYGLFLT3 | |
| SCHEMBL23716167 | 0.63 | FFAR2 (0.47) | NPC1 | |
| SCHEMBL18886853 | 0.62 | KMT2A (0.54) | SIRT1F7F3PYGLFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |