Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 4/20 | 0.44 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | OGG1 | O15527 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716421 | 0.80 | S1PR3 (0.68) | S1PR3S1PR2S1PR4S1PR1 | |
| SCHEMBL23716111 | 0.76 | OGG1 (0.45) | SYKOGG1TRPM8 | |
| SCHEMBL23716193 | 0.73 | OGG1 (0.44) | CNR1CNR2OGG1POLB | |
| SCHEMBL13710935 | 0.72 | ROCK2 (0.48) | SYKOGG1TRPM8ADRB2ADRB1 | |
| SCHEMBL23716154 | 0.72 | ROCK2 (0.48) | SYKOGG1TRPM8ADRB2ADRB1 | |
| SCHEMBL17664004 | 0.72 | S1PR3 (0.54) | S1PR3S1PR2S1PR4S1PR1SYK | |
| SCHEMBL23715916 | 0.70 | OGG1 (0.44) | OGG1TRPM8 | |
| SCHEMBL17664005 | 0.70 | S1PR3 (0.49) | S1PR3S1PR2S1PR4S1PR1SYK | |
| SCHEMBL13707887 | 0.70 | ALDH1A1 (0.49) | S1PR3S1PR2S1PR4SYKOGG1 | |
| SCHEMBL22758107 | 0.68 | TRPM8 (0.47) | TRPM8ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3209732-B1 | SPHINGOSINE-1-PHOSPATE RECEPTOR MODULATORS FOR TREATMENT OF CARDIOPULMONARY DISORDERS | SCRIPPS RESEARCH INST (US) | 2021-08-04 | — | — | EP | disclosed |