Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23185057 | 0.84 | MAOA (0.38) | ALDH1A1KIF11CYP3A4SMN1; SMN2MEN1 | |
| SCHEMBL17974865 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TAAR1KIF11CYP1A2CYP3A4 | |
| SCHEMBL18372417 | 0.83 | ALDH1A1 (0.41) | ALDH1A1TAAR1KIF11CYP1A2CYP3A4 | |
| SCHEMBL15447619 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TAAR1KIF11CYP1A2CYP3A4 | |
| SCHEMBL17974867 | 0.75 | RXRA (0.37) | CYP3A4SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL24206102 | 0.72 | KIF11 (0.46) | KIF11SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL18352212 | 0.72 | KIF11 (0.46) | KIF11SMN1; SMN2MEN1KMT2ARAB9A | |
| SCHEMBL24433604 | 0.71 | ALDH1A1 (0.43) | ALDH1A1TAAR1KIF11CYP1A2CYP3A4 | |
| SCHEMBL21105952 | 0.71 | HSD17B1 (0.43) | ALDH1A1CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6723658 | 0.70 | CHKA (0.53) | ALDH1A1TAAR1CYP1A2CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | ALDH1A1 227/4885TAAR1 171/4885KIF11 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.