Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763055 | 0.78 | MAPK1 (0.62) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL14275260 | 0.73 | KMT2A (0.58) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL9473296 | 0.69 | GSK3A (0.63) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL10688435 | 0.69 | KMT2A (0.53) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL29062452 | 0.67 | PGR (0.50) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL6884230 | 0.67 | PGR (0.54) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL12220558 | 0.66 | KMT2A (0.49) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL14518042 | 0.65 | ALDH1A1 (0.59) | MAPK1ALDH1A1LMNANPSR1TSHR | |
| SCHEMBL783401 | 0.64 | BRD4 (0.49) | KMT2AMAPK1KDM4EALDH1A1LMNA | |
| Triphenylene SCHEMBL27947419 | 0.63 | CES2 (0.50) | KMT2AKDM4EALDH1A1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 2022-01-27 | — | — | US | disclosed |
| US-20210244740-A1 | INHIBITORS OF RSV REPLICATION AND APPLICATIONS THEREOF | EMORY UNIVERSITY | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244740-A1 | INHIBITORS OF RSV REPLICATION AND APPLICATIONS THEREOF | SNRPE, PRDX1, PRDX6 | KMT2A 3999/4885MAPK1 2851/4885KDM4E 3946/4885 |
| US-20220023270-A1 | ANTIBACTERIAL COMPOUNDS AND USES THEREOF | CLPP, SPOUT1, MRPL21 | KMT2A 4413/4885MAPK1 3903/4885KDM4E 4451/4885 |
| US-12016863-B2 | Inhibitors of RSV replication and applications thereof | SNRPE, PRDX1, PRDX6 | KMT2A 3999/4885MAPK1 2851/4885KDM4E 3946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.