SCHEMBL23746003

SCHEMBL23746003

C#CCNC(=O)c1ccc(SC/C(F)=C/CNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
NAMPT P43490 3/20 0.35
EGFR P00533 1/20 0.34
CD274 Q9NZQ7 1/20 0.33
ALDH1A1 P00352 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
EPHX2 P34913 2/20 0.32
NR1H4 Q96RI1 2/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
PKM P14618 1/20 0.32
TSHR P16473 1/20 0.32
USP2 O75604 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23723309 0.85 CA2 (0.43) CA12CA1CA2CA9CA14
SCHEMBL23723241 0.85 MAPT (0.43) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL23723242 0.85 MAPT (0.43) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL23723307 0.85 CA2 (0.43) CA12CA1CA2CA9CA14
SCHEMBL30633634 0.84 RAB9A (0.44) NPC1RAB9AALDH1A1MEN1KMT2A
SCHEMBL30633638 0.83 ALDH1A1 (0.34) CA12CA1CA2CA9NPC1
SCHEMBL21693480 0.82 BRD4 (0.36) RAB9AALDH1A1EPHX2NR1H4MAPT
SCHEMBL26758437 0.81 IDO1 (0.41) CA12CA1CA14NPC1RAB9A
SCHEMBL23746004 0.81 CA1 (0.48) CA12CA1CA2CA9CA14
SCHEMBL23723262 0.75 APEX1 (0.48) NPC1RAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO CA12 1829/4885CA1 1688/4885CA2 1164/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 CA12 2655/4885CA1 3371/4885CA2 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.