Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 known ✓ | P08235 | 1/20 | 0.32 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.30 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ENTPD1 | P49961 | 1/20 | 0.31 |
| ▸ | ENTPD2 | Q9Y5L3 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37571 | 0.97 | NR1I2 (0.35) | NR1I2NR3C1PGRNR3C2GPR84 | |
| SCHEMBL29460462 | 0.97 | NR1I2 (0.35) | NR1I2NR3C1PGRNR3C2GPR84 | |
| SCHEMBL6023749 | 0.86 | GPR35 (0.34) | NR1I2NR3C1PGRNR3C2GPR84 | |
| SCHEMBL29364308 | 0.84 | CYP2D6 (0.43) | NR3C1PGRNR3C2GPR84CYP2D6 | |
| SCHEMBL29720 | 0.84 | CYP2D6 (0.43) | NR3C1PGRNR3C2GPR84CYP2D6 | |
| SCHEMBL10659453 | 0.83 | CYP2D6 (0.43) | NR3C1PGRNR3C2GPR84CYP2D6 | |
| SCHEMBL7559395 | 0.83 | CA2 (0.35) | NR3C1PGRNR3C2HTR2APARP1 | |
| Ammonia Solution, Strong SCHEMBL23749174 | 0.83 | CYP2D6 (0.43) | NR3C1PGRNR3C2GPR84CYP2D6 | |
| SCHEMBL10890143 | 0.83 | CYP2D6 (0.43) | NR3C1PGRNR3C2GPR84CYP2D6 | |
| SCHEMBL9219851 | 0.82 | RECQL (0.44) | NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3864963-A1 | OILY SUSPENSION AGROCHEMICAL COMPOSITION | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-08-18 | — | — | EP | disclosed |