SCHEMBL23768009

SCHEMBL23768009

C[N+](C)=C1C=CC2=Nc3ccc(N4CCOCC4)cc3[Si](C)(C)C2=C1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGMN Q99538 1/20 0.32
PRKDC P78527 2/20 0.32
MAPT P10636 8/20 0.32
TP53 P04637 3/20 0.32
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 3/20 0.32
MAPK1 P28482 2/20 0.32
ALOX15 P16050 2/20 0.32
HSD17B10 Q99714 2/20 0.32
HTT P42858 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
KMT2A Q03164 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 3/20 0.31
HPGD P15428 2/20 0.31
PDE3B Q13370 1/20 0.31
PDE3A Q14432 1/20 0.31
MITF O75030 1/20 0.31
NTSR1 P30989 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23768045 0.89 TERT (0.32) HPGDPDE3BPDE3A
SCHEMBL23767938 0.89 LMNA (0.31) LGMNPRKDCMAPTALDH1A1MAPK1
SCHEMBL23768028 0.87 ALDH1A1 (0.32) LGMNPRKDCMAPTALDH1A1MAPK1
SCHEMBL23768026 0.87 LMNA (0.31) LGMNPRKDCMAPTALDH1A1MAPK1
SCHEMBL23768027 0.87 PDE3B (0.31) LGMNPRKDCMAPTALDH1A1PDE3B
SCHEMBL23768005 0.86 PIK3CD (0.33) PRKDCMAPTALDH1A1KDM4EMEN1
SCHEMBL23768010 0.86
SCHEMBL22972949 0.86 PRKDC (0.36) LGMNPRKDCMAPTTP53ALDH1A1
SCHEMBL23768072 0.85 MEN1 (0.32) MAPTALDH1A1HTTMEN1KMT2A
SCHEMBL23768073 0.85 PIK3CA (0.34) PRKDCMAPTALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX LGMN 2874/4885PRKDC 1574/4885MAPT 322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.