SCHEMBL23767938

SCHEMBL23767938

CC[N+](CC)=C1C=CC2=Nc3ccc(N4CCOCC4)cc3[Si](C)(C)C2=C1

nearest known ligand 0.31

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 2/20 0.31
MAPK1 P28482 2/20 0.31
LGMN Q99538 1/20 0.30
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
TMEM97 Q5BJF2 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
PRKDC P78527 1/20 0.30
AGXT P21549 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23768175 0.90 TERT (0.30)
SCHEMBL23768024 0.89 LMNA (0.31) LMNAHPGDSMN1; SMN2MAPTMAPK1
SCHEMBL23768009 0.89 LGMN (0.32) LMNAHPGDSMN1; SMN2MAPTMAPK1
SCHEMBL23767945 0.89
SCHEMBL23768023 0.87 BRD4 (0.30) LMNASMN1; SMN2
SCHEMBL23768022 0.87 ALDH1A1 (0.32) MAPTMAPK1ALDH1A1
SCHEMBL23767940 0.87 TMEM97 (0.33) LMNAHPGDSMN1; SMN2MAPTADRA2A
SCHEMBL23768047 0.86 MEN1 (0.31) HPGDMAPTALDH1A1
SCHEMBL23768044 0.86 SIGMAR1 (0.34) LMNAHPGDSMN1; SMN2MAPTADRA2A
SCHEMBL22972949 0.83 PRKDC (0.36) HPGDSMN1; SMN2MAPTMAPK1LGMN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS ORTA DOGU TEKNIK UNIVERSITESI (TR) 2021-08-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210252152-A1 NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS PPIF, MT-ND2, PPOX LMNA 2303/4885HPGD 424/4885SMN1; SMN2 3094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.