Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770657 | 0.87 | HRH3 (0.33) | NPC1 | |
| SCHEMBL29464308 | 0.79 | KMO (0.34) | NPC1 | |
| SCHEMBL19968825 | 0.79 | KMO (0.34) | NPC1 | |
| SCHEMBL23770559 | 0.77 | HRH3 (0.34) | — | |
| SCHEMBL23770589 | 0.76 | WDR5 (0.31) | — | |
| SCHEMBL23770441 | 0.74 | HTR3E (0.43) | CNR1CNR2 | |
| SCHEMBL23770622 | 0.72 | CTSL (0.36) | — | |
| SCHEMBL23770593 | 0.70 | GALR2 (0.33) | NPC1 | |
| SCHEMBL23770787 | 0.69 | PDE10A (0.35) | CNR2 | |
| SCHEMBL23770598 | 0.68 | ADRB2 (0.43) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |