Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23770705 | 0.73 | HRH3 (0.35) | — | |
| SCHEMBL23770657 | 0.72 | HRH3 (0.33) | ABL1 | |
| SCHEMBL19927702 | 0.72 | SCN1A (0.33) | ABL1 | |
| SCHEMBL23770622 | 0.69 | CTSL (0.36) | — | |
| SCHEMBL23770496 | 0.69 | RAF1 (0.35) | ABL1 | |
| SCHEMBL23770454 | 0.69 | PIM1 (0.34) | ABL1 | |
| SCHEMBL23770744 | 0.68 | RAF1 (0.33) | ABL1 | |
| SCHEMBL23770643 | 0.68 | ADRB2 (0.37) | ABL1 | |
| SCHEMBL23770589 | 0.68 | WDR5 (0.31) | — | |
| SCHEMBL23770679 | 0.68 | TTR (0.32) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504194-B1 | N-(PYRIDIN-2-YL)PYRIDINE-SULFONAMIDE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASE | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |