SCHEMBL2377424

SCHEMBL2377424

O=C(C=CC1C=CC(O)=CC1)NCCc1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MMP1 P03956 3/20 0.46
MMP2 P08253 3/20 0.46
MMP9 P14780 3/20 0.46
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
KDM4E B2RXH2 1/20 0.43
F13A1 P00488 1/20 0.43
TAAR1 Q96RJ0 2/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15313023 0.81 MMP1 (0.46) MMP1MMP2MMP9BCHEACHE
SCHEMBL2377831 0.79 MET (0.52)
SCHEMBL15313125 0.77 ALDH1A1 (0.45) MMP1MMP2MMP9BCHEACHE
SCHEMBL8269511 0.70 KDM4E (0.62) MMP1MMP2MMP9BCHEACHE
SCHEMBL2023110 0.70 CYP3A4 (0.47) MMP1MMP2MMP9KDM4EALDH1A1
SCHEMBL31437614 0.70
N-P-Coumaroyl Tyramine SCHEMBL19551426 0.69 MMP1 (0.86) MMP1MMP2MMP9BCHEACHE
N-P-Coumaroyl Tyramine SCHEMBL2512193 0.69 MMP1 (0.86) MMP1MMP2MMP9BCHEACHE
SCHEMBL2022647 0.68 MEN1 (0.41)
SCHEMBL18297852 0.67 KDM4E (0.57) MMP1MMP2MMP9BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9089499-B2 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions UNIVERSITE JOSEPH FOURIER-GRENOBLE 1 (FR) 2015-07-28 US disclosed
US-20130272983-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions Universite Joseph Fourier-Grenoble 1. (FR) 2013-10-17 US disclosed
US-8481593-B2 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions BASF BEAUTY CARE SOLUTIONS S.A.S. (FR) 2013-07-09 US disclosed
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2011-09-29 US disclosed
US-20070183996-A1 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions BASF BEAUTY CARE SOLUTIONS FRANCE S.A.S. (FR) 2007-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110237551-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and Their Use in Cosmetic or Dermatological Compositions TYR, CUTA, HPD MMP1 498/4885MMP2 360/4885MMP9 553/4885
US-20070183996-A1 Para-coumaric acid or para-hydroxycinnamic acid derivatives and their use in cosmetic or dermatological compositions TYR, CUTA, HPD MMP1 546/4885MMP2 398/4885MMP9 605/4885
US-20130272983-A1 Para-Coumaric Acid or Para-Hydroxycinnamic Acid Derivatives and their Use in Cosmetic or Dermatological Compositions TYR, CUTA, HPD MMP1 546/4885MMP2 398/4885MMP9 605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.