SCHEMBL23778657

SCHEMBL23778657

CCCC(=O)NCCc1c[nH]c(-c2ccc(Oc3ccccc3)cc2)n1

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 2/20 0.46
MTNR1B P49286 1/20 0.46
EPHX2 P34913 3/20 0.43
TSHR P16473 1/20 0.42
ADORA3 P0DMS8 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
LTA4H P09960 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778719 0.90 ADORA1 (0.50) MTNR1AMTNR1BTSHRADORA3ADORA2A
SCHEMBL23778696 0.88 MTNR1A (0.50) MTNR1AMTNR1BTSHRLMNA
SCHEMBL23778716 0.86 MTNR1A (0.45) MTNR1AMTNR1BTSHRADORA3ADORA2A
SCHEMBL23778721 0.84 ADORA3 (0.45) MTNR1AMTNR1BTSHRADORA3ADORA1
SCHEMBL23778693 0.83 HPGD (0.58) ADORA3ADORA2AADORA1LMNATP53
SCHEMBL23778733 0.83 THRB (0.45) MTNR1ATSHRADORA3LMNATP53
SCHEMBL23778715 0.82 MTNR1A (0.48) MTNR1AMTNR1BTSHRADORA3ADORA2A
SCHEMBL23778706 0.82 HPGD (0.43) MTNR1AMTNR1BTSHR
SCHEMBL23778678 0.80 HPGD (0.40) MTNR1AMTNR1BTSHRTP53
SCHEMBL23778705 0.76 GSK3B (0.41) MTNR1AMTNR1BTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 MTNR1A 1790/4885MTNR1B 1398/4885EPHX2 2655/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 MTNR1A 306/4885MTNR1B 455/4885EPHX2 2743/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 MTNR1A 2087/4885MTNR1B 1749/4885EPHX2 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.