SCHEMBL23778696

SCHEMBL23778696

CCCC(=O)NCCc1c[nH]c(-c2ccc(OC)cc2)n1

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 6/20 0.50
MTNR1B P49286 6/20 0.50
KDM4E B2RXH2 1/20 0.49
TSHR P16473 1/20 0.49
HSD17B10 Q99714 1/20 0.49
THRB P10828 1/20 0.48
LMNA P02545 1/20 0.48
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23778657 0.88 MTNR1A (0.46) MTNR1AMTNR1BTSHRLMNA
SCHEMBL23778721 0.87 ADORA3 (0.45) MTNR1AMTNR1BKDM4ETSHRHSD17B10
SCHEMBL23778693 0.86 HPGD (0.58) LMNA
SCHEMBL23778733 0.86 THRB (0.45) MTNR1ATSHRTHRBLMNAALDH1A1
SCHEMBL23778719 0.85 ADORA1 (0.50) MTNR1AMTNR1BTSHRLMNA
SCHEMBL23778706 0.84 HPGD (0.43) MTNR1AMTNR1BTSHRALDH1A1
SCHEMBL23778678 0.83 HPGD (0.40) MTNR1AMTNR1BTSHRHSD17B10ALDH1A1
SCHEMBL23778716 0.82 MTNR1A (0.45) MTNR1AMTNR1BTSHRALDH1A1
SCHEMBL23778705 0.79 GSK3B (0.41) MTNR1AMTNR1BKDM4ETSHRHSD17B10
SCHEMBL23778643 0.78 MTNR1A (0.47) MTNR1AKDM4EHSD17B10THRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US claimed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP claimed
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2026-01-01 US disclosed
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof AHAMMUNE BIOSCIENCES PRIVATE LIMITED (IN) 2025-08-05 US disclosed
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF AHAMMUNE BIOSCIENCES PRIVATE LTD (IN) 2021-12-09 US disclosed
EP-3873890-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF Ahammune Biosciences Private Limited (IN) 2021-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380538-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF IDO1, IDO2, NFATC1 MTNR1A 1790/4885MTNR1B 1398/4885KDM4E 985/4885
US-20260001850-A1 NOVEL IMIDAZOLE COMPOUNDS, PROCESS FOR THE SYNTHESIS AND USES THEREOF MALT1, ADRM1, CYP11B1 MTNR1A 306/4885MTNR1B 455/4885KDM4E 4085/4885
US-12378203-B2 Imidazole compounds, process for the synthesis and uses thereof IDO1, IDO2, NFATC1 MTNR1A 2087/4885MTNR1B 1749/4885KDM4E 841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.